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KMID : 1094020170340060401
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Journal of Veterinary Clinics
2017 Volume.34 No. 6 p.401 ~ p.403
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D-dimer Analysis in Dogs With Hypercoagulable Diseases
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Ku Ta Liang
Park Hyung-Jin
Seo Kyoung-Won
Song Kun-Ho
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Abstract
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Total 283 dogs were enrolled in this study (control group: 140, patient group: 143). In the patient group, 143 dogs with underlying diseases including immune medicated hemolytic anemia (IMHA) (7), lymphoma (30), hyperadrenocorticism (HAC) (16), trauma (10), pyometra (8), bone fracture (38), peritonitis (13), meningoencephalitis (12) and mitral regurgitation (9) were enrolled in this study. Compared with healthy group, lymphoma, trauma, HAC, and IMHA group showed significantly (P < 0.01) high values of D-dimer and the highest levels in the IMHA group. Additionally, we evaluated the D-dimer level after a week of enoxaparin treatment, and the results showed D-dimer levels of post treatment group were significantly decreased compared to the pre-treatment group in lymphoma, HAC, trauma and IMHA diseases. In the high level D-dimer group, post D-dimer values after enoxaparin treatment had significantly decreased (P < 0.01) compared to levels prior to treatment.
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KEYWORD
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D-dimer, dog, enoxaparin, levels, underlying diseases
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